From $49.00
Solace™ is a product that was developed with much excitement and care to make sure the blend was perfect. We spent many months working with various extracts of from the raw Corydalis Yanhusuo Stem. We combined this with G for added Relaxation and Comfort support as well as Curcumin to support liver health while taking corydalis. This product also contains the plant terpenes: Myrcene, Linalool, Humulene and AP0-808 Probiotic Blend and SRT Polysaccharide Complex for improved absorption.
Precautions Before Using Corydalis:
More research is needed to learn about the possible side effects of using corydalis supplements with other herbs, supplements, or medications. Talk to your healthcare provider before you start taking corydalis, especially if you are already taking other prescription or over-the-counter (OTC) medications, supplements, or products. There has not been enough safety and effectiveness research on corydalis use in certain groups of people who might be at risk for side effects. Children should not take corydalis. In addition, adults should steer clear if they are Pregnant or Breastfeeding or a history of seizures. Studies show it can be safe to take for at least 4 weeks and possibly longer however speak to to health care provider before taking it longer than one month. Consuming corydalis can have side effects. There is a risk of THP toxicity from corydalis supplements show in animal studies at over 475mg/kilogram of body weight. With an average body weight of an adult at 70 kilo that’s 33 grams of the THP alkaloid and this product contains 100mg of THP. In high doses THP can cause sever liver stress (acute hepatitis), the symptoms of which are nausea, vomiting, pain in the abdomen, or fever. Ref So don’t take high doses and Solace is meant for short term use of less then 4 weeks.
| Solace Bullets- Package Amounts |
Solace Bullet #5 ,Solace Bullet #15 |
|---|
Dosage and Storage Instructions: Store in refrigeration.
Bullets Per Serving size: 1 Serving: 15 Amount Per Serving % Daily Value
Proprietary Blend:
Corydalis Extract containing 98% THP 100mg *
Hemp / Full Spectrum 20mg
Curcumin / Boswellia *****
Terpenes: Myrcene, Linalool, Humulene *****
AP0-808 Probiotic Blend *****
SRT Polysaccharide Complex. *****
Organic Palm Oil *****
****Daily Value not established****
Preliminary reports from Chinese researchers also note that 75 mg per day of THP (an alkaloid from the plant corydalis) was effective in reducing nerve pain in 78% of those tested.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8704877/
Corydalis contains several ingredients, one of which has been shown to influence the nervous system, promoting relaxation.
Corydalis contains several ingredients, one of which has been shown to influence the nervous system, providing pain relief and promoting relaxation. People with insomnia were able to fall sleep more easily after taking 100 to 200 mg per day of a corydalis extract (called dl-tetrahydropalmatine, or DHP), according to a preliminary report.People taking the extract reported no drug hangover symptoms, such as dizziness or vertigo
An active constituent in corydalis, dl-tetrahydropalmatine, may have an anti-arrhythmic effect on the heart.
An active constituent in corydalis, dl-tetrahydropalmatine (dl-THP), may exert an anti-arrhythmic action on the heart. This action was observed in a preliminary trial with 33 patients suffering from a specific type of arrhythmia called supraventricular premature beat or SVPB. Each patient took 300 to 600 mg of dl-THP per day in tablet form, and the dl-THP was found to be significantly more effective than placebo in reducing arrhythmia.
A constituent of corydalis called tetrahydropalmatine appears to heave pain-relieving and sedative effects. It has shown to be effective for painful menstruation.
Corydalis contains several alkaloids, and one called tetrahydropalmatine (THP) is considered to be the most potent. In laboratory research, THP has been shown to exhibit a wide number of pharmacological actions on the central nervous system, including pain-relieving and sedative effects. According to a secondary reference, painful menstruation responded favorably to the administration of THP. For a pain-relieving effect, the recommended amount for the crude dried rhizome is 5–10 grams per day. Alternatively, one can take 10–20 ml per day of a 1:2 extract.
Corydalis extracts are useful in relieving pain and in treating stomach ulcers.
Extracts of the herb corydalis are not only helpful as pain-relief agents but also may be useful in the treatment of stomach ulcers. In a study of people with stomach and intestinal ulcers or chronic inflammation of the stomach lining, 90 to 120 mg of corydalis extract per day (equal to 5 to 10 grams of the crude herb) was found to be effective in 76% of the participants.
Based on previous clinical and animal trials, oral administration of raw C. yanhusuoextracts (more than 1–3 g/day) or total C. yanhusuo alkaloids (473.36 mg/kg) induced liver damage, muscle tremors, and renal hemorrhage in mice, indicating that raw C. yanhusuo extracts and total C. yanhusuo alkaloids have mild toxicity Ref. The liver damage may be due to the effects of high-dose C. yanhusuo including disordered energy metabolism and increased hepatocyte membrane permeability that facilitated the release of intracellular transaminase into the blood, eventually leading to liver cell swelling, acid change, necrosis, and inflammatory cell infiltration Ref. However, the mechanism through which C. yanhusuo induces muscle tremor and renal hemorrhage has not been reported, and therefore, further studies are needed.
The hepatotoxicity of total alkaloids in C. yanhusuo can be reduced by adding Curcumae longa or Curcumin. This is why we added this to our formula.
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WARNINGS: Although safe for children, this product should be kept out of the reach of children. Do not use it if the package is open or damaged. As with any nutrient, if you are pregnant or breastfeeding, seek the advice of a health care provider before using this product.
This product can be taken safely by mouth. According to FDA regulations this product is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).
FOOD AND DRUG ADMINISTRATION (FDA) DISCLOSURE
*THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FOOD AND DRUG ADMINISTRATION. THIS PRODUCT IS NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE.
Disclaimer: These statements have not been evaluated by the FDA. In accordance with FDA regulations, this product can be taken orally, this product and is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff).This product is a Federal Food, Drug, and Cosmetic Act-compliant combination of naturally derived FDA GRAS (Generally regarded As Safe) herbal, nutraceutical, vitamins, minerals, and amino acids products legally sold in the USA. According to FDA regulations this product is considered a dietary supplement as defined by section 201(ff) of the Act, 21 U.S.C. § 321(ff). MitoZen PMA’s product line is a naturally derived FDA GRAS (Generally regarded As Safe) mineral, herbal, vitamins, and nutraceutical products that can be legally sold in the USA. MitoZen PMA products are not a drug as defined in section 201(g)(1) of the Act, 21 U.S.C. § 321(g)(1). MitoZen’s products are not intended to affect the structure or function of the body and are not intended for use in the diagnosis, cure, mitigation, treatment, or prevention of disease in man. Any nutritional suggestions and research regarding this product are provided for informational purposes only, and are not intended to diagnose, treat, cure, or prevent disease nor should any information provided be used as a substitute for sound medical advice. This product is not for use by or sale to persons under the age of 18. This product should be used only as directed on the label. It should not be used if you are pregnant or nursing. Consult with a physician before use, if you have a serious medical condition or use prescription medications. A Doctor’s advice should be sought before using this and any supplemental dietary product. All trademarks and copyrights are the property of their respective owners, and are not affiliated with nor do they endorse this product. These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease. By using this site you agree to follow the Privacy Policy and Terms & Conditions printed on this site. Void Where Prohibited By Law.
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During the hot summer months, we recommend taking advantage of the cold shipping option to ensure product stability upon arrival.
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